A REVIEW OF PKRRATING

3B). R526 from the loop amongst αJ and αI anchors the C-terminal portion of the activation loop by forming a salt bridge with E458 at the base of αEF. Q459 stabilizes the HRD motif by a hydrogen bond to the primary chain carbonyl of R413. The idea in the activation section is stabilized by a hydrogen bond amongst Y454 and E480 from αfile. while